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ACRP ACRP-CP Exam Syllabus Topics:
| Section | Objectives |
|---|---|
| Topic 1: Participant Safety and Protection | - Safety reporting and adverse events - Informed consent process |
| Topic 2: Data and Quality Management | - Quality assurance and quality control - Clinical data management principles |
| Topic 3: Study Operations | - Study planning and initiation - Study conduct and oversight |
| Topic 4: Clinical Research Foundations | - Good Clinical Practice (GCP) principles - Ethical conduct in clinical trials |
| Topic 5: Regulatory Compliance | - Audit and inspection readiness - Regulatory documentation and submissions |
ACRP Certified Professional Sample Questions:
1. Who determines the age of assent for pediatric studies?
A) IRB/IEC
B) PI
C) Parent
D) Sponsor
2. The coding system for a double-blind clinical trial is accessible by the:
A) Regulatory authority
B) IRB/IEC
C) PI
D) Sponsor
3. A PI is reviewing the CRF for a recent subject visit and notices the participant's heart rate and temperature are not recorded. Which of the following study documentation practices was neglected?
A) Original
B) Complete
C) Contemporaneous
D) Attributable
4. Which of the following should be considered when implementing a risk-based monitoring plan?
A) 100% source document review is mandatory.
B) On-site monitoring frequency may change depending on the quality of the data.
C) Monitoring schedule must be pre-defined in the monitoring plan.
D) Centralized monitoring must be incorporated in any trials.
5. When designing a clinical trial, why is it important to define the study population?
A) To support subject recruitment to the study
B) To determine where to conduct the study
C) To determine the study objectives
D) To support the study objectives
Solutions:
| Question # 1 Answer: A | Question # 2 Answer: D | Question # 3 Answer: B | Question # 4 Answer: B | Question # 5 Answer: D |



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